Prof. Luis Rocha from CNETS at IU Bloomington, Prof. Lang Li from IUPUI Medical School, and Prof. Hagit Shatkay from the University of Delaware have been awarded a four-year, $1.7M grant from NIH/NLM to study the large-scale extraction of drug-Interaction from medical text. Drug-drug interaction (DDI) leads to adverse drug reactions, emergency room visits and hospitalization, thus posing a major challenge to public health. To circumvent risk to patients, and to expedite biomedical research, both clinicians and biologists must have access to all available knowledge about potential DDI, and understand both causes and consequences of such interactions. However, mere identification of interactions does not directly support such understanding, as evidence for DDI varies broadly, from reports of molecular interactions in basic-science journals, to clinical descriptions of adverse-effects in a myriad of medical publications. This project will develop tools that focus directly on large-scale identification and gathering of various types of reliable experimental evidence of DDI from diverse sources. The successful completion of the project will provide clinicians and biologists with substantiated knowledge about drug interactions and with informatics tools to obtain such information on a large-scale, laying the basis for preventing adverse drug reactions and for exploring alternative treatments.
The National Institutes of Health has given $1.2 million to Indiana University researchers to build the ultimate international epidemic research tool. Principle investigators Katy Börner, Steven J. Sherman and Alessandro Vespignani will oversee the project, EpiC, which they hope will make the sharing and re-using of epidemics datasets and algorithms as easy as sharing videos via YouTube. The three researchers come from three distinct areas of the campus — the School of Library and Information Science, the Department of Psychological and Brain Sciences in the College of Arts and Sciences, and the School of Informatics, respectively. Additional members of the evolving team are IU researchers Duygu Balcan, Weixia Huang and Bruce W. Herr. Read the full press release or more info and figures….